Spontaneous Remission in Congenital Leukemia AML-M1 with Pericardial Effusion

Spontaneous Remission in Congenital Leukemia AML-M1 with Pericardial Effusion

Congenital leukemia is a very rare malignancy of childhood with a poor prognosis. The incidence is nearly 1 in 5 million live births. The majority of cases are acute myeloblastic leukemia with trisomy. Clinical manifestations are usually leukocytosis, petechia, ecchymosis, cutaneous nodules, hepatosplenomegaly and central nervous system symptoms. 23-days old girl was presented with complaints o...

Spontaneous remission of granulocyte colony-stimulating factor-associated leukemia in a child with severe congenital neutropenia.

Leukemia is observed with increased frequency in patients with severe congenital neutropenia (SCN). In the past decade, recombinant human granulocyte colony-stimulating factor (rh G-CSF) has prolonged the survival of patients with SCN increasingly reported to have leukemias. In this communication acute myelogenous leukemia (AML) associated with a mutation of the G-CSF receptor (G-CSF-R) develop...

Spontaneous remission in hypoplastic acute leukemia.

A recurrent spontaneous complete remission of acute hypoplastic leukemia was observed. The remission occurred after a severe infection which was treated with antibiotics. Reports of spontaneous remission of acute leukemia in adults have become increasingly rare, and the remissions themselves are short-lived. Such spontaneous complete remissions are almost always associated with bacte rial infec...

Spontaneous remission of congenital acute myeloid leukemia with t(8;16)(p11;13).

To The Editor: We report a case of congenital acute myeloid leukemia (AML) with t(8;16) that went into spontaneous remission. A full-term female presented with blueberry muffin spots at birth. A skin biopsy revealed a diffuse dermal infiltration by immature hematopoietic cells and was diagnosed as myelosarcoma (Fig. 1A and B). At Day 10, the patient’s bone marrow showed 32.8% leukemic blasts (F...

Pericardial effusion.